发明名称 |
PEPTIDE INHIBITORS OF NICOTINIC ACETYLCHOLINE RECEPTOR |
摘要 |
The present invention refers to biochemistry, namely to new peptide compounds having the ability to selectively block the muscle-type nicotinic acetylcholine receptor. The claimed compounds have common formula (I): X1-X2-X3-Pro-X4-Pro-X5 (SEQ ID NO: 54), where X1 is chosen within H, Ac—, Palm-; X2 is chosen within Trp, Tyr; X3 is chosen within Trp, Tyr; X4 is chosen within Lys, Orn, Dbu, Dpr, Arg; X5 is chosen within —OH, —NH2, —OCH3, —OC2H5, —NH—C6H5. The invention can be applied in cosmetics for smoothing mimic and age-related Wrinkles. |
申请公布号 |
EP2945963(A1) |
申请公布日期 |
2015.11.25 |
申请号 |
EP20140740563 |
申请日期 |
2014.01.20 |
申请人 |
LIMITED LIABILITY COMPANY "SYNEURO" |
发明人 |
ZHMAK, MAXIM NURGAYANOVICH;UTKIN, YURY NIKOLAEVICH;ANDREEVA, TATYANA VIKTOROVNA;KUDRYAVTSEV, DENIS SERGEEVICH;KRYUKOVA, ELENA VIKTOROVNA;TSETLIN, VIKTOR IONOVICH;KASHEVEROV, IGOR EVGEN`EVICH;STARKOV, VLADISLAV GENNAD`EVICH;SHELUKHINA, IRINA VALER`EVNA |
分类号 |
C07K7/06;A61K8/02;A61K8/30;A61K8/44;A61K8/64;A61K38/00;A61K38/08;A61Q19/08;C07K14/705 |
主分类号 |
C07K7/06 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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