| 发明名称 | Adrenomedullin production enhancer | ||
| 摘要 | It is an object of the invention to discover a substance that effectively increases the production of adrenomedullin, as well as to provide an adrenomedullin production-enhancing agent utilizing this substance. The adrenomedullin production-enhancing agent is characterized by inclusion of a ginsenoside, a sanshool, and/or a shogaol as active ingredients. | ||
| 申请公布号 | US9193756(B2) | 申请公布日期 | 2015.11.24 |
| 申请号 | US200812918437 | 申请日期 | 2008.02.19 |
| 申请人 | National University Corporation ASAHIKAWA MEDICAL COLLEGE;TSUMURA & Co. | 发明人 | Kono Toru;Kaneko Atsushi;Omiya Yuji |
| 分类号 | A61K31/704;A61K31/164;C07J9/00;A61K36/75;A61K36/9068;C07J17/00 | 主分类号 | A61K31/704 |
| 代理机构 | Oblon, McClelland, Maier & Neustadt, L.L.P. | 代理人 | Oblon, McClelland, Maier & Neustadt, L.L.P. |
| 主权项 | 1. A method of increasing blood flow inside the intestinal tract, the method comprising administering to a subject in need thereof an effective amount of a composition comprising, as the only active ingredients, a hydroxysanshool and at least one of compound selected from the group consisting of ginsenoside Rb1 and ginsenoside Rg1 wherein the dosage ratio of the least one of compound selected from the group consisting of ginsenoside Rb1 and ginsenoside Rg1 to the hydroxysanshool is 10:3. | ||
| 地址 | Asahikawa-shi JP | ||