| 发明名称 |
Ketorolac tromethamine compositions for treating or preventing ocular pain |
| 摘要 |
The present invention provides an aqueous ophthalmic solution with an effective amount of ketorolac and carboxymethyl cellulose in an aqueous solution which provides increased visual acuity and wherein the concentration of carboxymethyl cellulose is selected to provide an increased absorption of ketorolac in the eye of a patient that is at least 130% greater than the absorption of a comparative aqueous ketorolac ophthalmic solution having the same concentration of ketorolac. |
| 申请公布号 |
US9192571(B2) |
申请公布日期 |
2015.11.24 |
| 申请号 |
US200912552057 |
申请日期 |
2009.09.01 |
| 申请人 |
Allergan, Inc. |
发明人 |
Farnes Eldon Q.;Attar Mayssa;Schiffman Rhett M.;Chang Chin-Ming;Graham Richard S.;Welty Devin F. |
| 分类号 |
A61K31/407;A61P27/02;A61K9/00;A61K9/08;A61K31/14;A61K47/02;A61K47/10;A61K47/12;A61K47/18;A61K47/38 |
主分类号 |
A61K31/407 |
| 代理机构 |
|
代理人 |
Siddiqi Lorenz |
| 主权项 |
1. A topical aqueous ophthalmic solution for use in treating pain or inflammation, wherein said solution comprises 0.45% w/v ketorolac and about 0.5% w/v carboxymethyl cellulose, with no preservative and having a pH within the range of approximately 6.8-7.4. |
| 地址 |
Irvine CA US |
