发明名称 Method for obtaining concentrated polyphenol extracts from a stirring process
摘要 The present invention proposes methods for obtaining concentrated polyphenol extracts resulting from the stirring process, through a step in which a partially purified beer is placed into contact with a resin that adsorbs the polyphenols, followed by a step in which the polyphenols adsorbed onto said resin are recovered. The invention also relates to the extracts thus obtained, which feature remarkable properties, as well as to several applications for these extracts.
申请公布号 US9193944(B2) 申请公布日期 2015.11.24
申请号 US200912937122 申请日期 2009.04.10
申请人 Brasseries Kronenbourg 发明人 Taidi Behnam;Doriat Jean-François;Malpote Jean-Yves
分类号 A61K36/00;A61K36/899;C12F3/06;A23L1/30;A61K8/97;A61Q19/08;C12H1/056 主分类号 A61K36/00
代理机构 Morgan, Lewis & Bockius LLP 代理人 Morgan, Lewis & Bockius LLP
主权项 1. A method of treating dry and/or aging skin comprising topically administering to a subject in need thereof a cosmetic product comprising an effective amount of a polyphenol concentrate, wherein the polyphenol concentrate comprises catechin, epicatechin, tyrosol and ferulic acid, and wherein the polyphenol concentrate is obtained from partially purified beer by a process comprising the steps of: (a) contacting partially purified beer containing polyphenols with a polyvinylpolypyrrolidone (PVPP) resin to adsorb the polyphenols to the resin,(b) washing the PVPP resin and adsorbed polyphenols with an alkaline solution to produce a PVPP washing solution,(c) contacting the PVPP washing solution with a second resin to adsorb the polyphenols to the second resin, the second resin being hydrophobic and nonionic,(d) passing an organic solvent over the second resin to desorb the polyphenols from the resin, and(e) collecting and concentrating the polyphenols to produce the polyphenol concentrate.
地址 Strasbourg FR