发明名称 |
Method for reversing recent-onset type 1 diabetes (T1D) by administering substance P (sP) |
摘要 |
Described herein is a treatment comprising the following step: (a) injecting a therapeutically effective amount of a pharmaceutical composition into the celiac artery of an individual, wherein the pharmaceutical composition reverses recent onset Type 1 Diabetes (T1D). Also described is a method for identifying an individual who will be responsive to this treatment. In addition there is described a device containing the pharmaceutical composition for injecting the pharmaceutical composition into the celiac artery. |
申请公布号 |
US9192647(B2) |
申请公布日期 |
2015.11.24 |
申请号 |
US201414244990 |
申请日期 |
2014.04.04 |
申请人 |
|
发明人 |
Dosch Hans-Michael |
分类号 |
A61K38/08;A61P3/10;A61K9/00;C12Q1/68 |
主分类号 |
A61K38/08 |
代理机构 |
Alchemy-Partners, PC |
代理人 |
Alchemy-Partners, PC |
主权项 |
1. A method comprising:
delivering a therapeutically effective amount of a pharmaceutical composition comprising substance P (sP) into celiac artery of an individual in need thereof to at least partially reverse recent onset type 1 diabetes (T1D) in the individual, wherein the therapeutically effective amount of the pharmaceutical composition comprises at least 10 nmol/kg of substance P. |
地址 |
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