发明名称 Method for reversing recent-onset type 1 diabetes (T1D) by administering substance P (sP)
摘要 Described herein is a treatment comprising the following step: (a) injecting a therapeutically effective amount of a pharmaceutical composition into the celiac artery of an individual, wherein the pharmaceutical composition reverses recent onset Type 1 Diabetes (T1D). Also described is a method for identifying an individual who will be responsive to this treatment. In addition there is described a device containing the pharmaceutical composition for injecting the pharmaceutical composition into the celiac artery.
申请公布号 US9192647(B2) 申请公布日期 2015.11.24
申请号 US201414244990 申请日期 2014.04.04
申请人 发明人 Dosch Hans-Michael
分类号 A61K38/08;A61P3/10;A61K9/00;C12Q1/68 主分类号 A61K38/08
代理机构 Alchemy-Partners, PC 代理人 Alchemy-Partners, PC
主权项 1. A method comprising: delivering a therapeutically effective amount of a pharmaceutical composition comprising substance P (sP) into celiac artery of an individual in need thereof to at least partially reverse recent onset type 1 diabetes (T1D) in the individual, wherein the therapeutically effective amount of the pharmaceutical composition comprises at least 10 nmol/kg of substance P.
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