发明名称 |
4-(5-aminometil-2-fluoro-fenil)-piperidin-1-il]-[7-fluoro-1-(2-metóxi-etil)-4-trifluorometóxi-1h-indol-3-il]-metanona como inibidor de triptase de mastócito, seu uso e método de preparação, bem como forma cristalina |
摘要 |
The present invention is directed to an indole benzylamine compound of formula I: useful as an inhibitor of tryptase. In addition, the present invention is directed to the use of the compound for treating a patient suffering from, or subject to, a physiological condition in need of amelioration by inhibition of tryptase, comprising administering to the patient of a therapeutically effective amount of the compound, and to a pharmaceutical composition comprising a pharmaceutically effective amount of the compound of formula I, and a pharmaceutically acceptable carrier. |
申请公布号 |
BRPI0916920(A2) |
申请公布日期 |
2015.11.24 |
申请号 |
BR2009PI16920 |
申请日期 |
2009.08.20 |
申请人 |
SANOFI-AVENTIS |
发明人 |
ADAM W. SLEDESKI;GREGORY BERNARD POLI;JOHN J. SHAY, JR;NAKYEN CHOY;PATRICK WAI-KWOK SHUM;YONG MI CHOI-SLEDESKI |
分类号 |
C07D401/06;A61K31/404;A61P29/00 |
主分类号 |
C07D401/06 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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