2,3-DIHYDROBENZOFURAN DERIVATIVES AS AN SGLT INHIBITOR AND PHARMACEUTICAL COMPOSITION COMPRISING SAME

摘要

The present invention relates to a compound selected from the group consisting of dihydrobenzofuran derivatives having an inhibitory activity against a sodium-dependent glucose transporter (SGLT), which is present in intestines and kidneys, and represented by a chemical formula 1 or a pharmaceutically acceptable salt thereof, an isomer, a hydrate, and a solvate, and a pharmaceutical composition containing the same as an active ingredient. The compound or pharmaceutical composition effectively inhibits activation of the SGLT, thereby being used as a therapeutic agent for diabetes including insulin-dependent diabetes mellitus (type I diabetes mellitus), non-insulin-dependent diabetes mellitus (type II diabetes mellitus), diabetic complications, diseases caused by hyperglycemia such as obesity and the like.