| 摘要 |
FIELD: chemistry.SUBSTANCE: group of inventions relates to devices and methods for analysis using specific binding and is intended for determining the presence or amount of an analyte in a sample. The immunochromatographic device comprises a membrane carrying a capture antibody bound thereto in a test zone, and a structure having conjugates, fluidly coupled to the membrane at a proximal end. The structure comprises a detector antibody having a reporter moiety conjugated therewith. Each of said capture and detector antibodies is a monoclonal antibody produced by hybridoma cells deposited under access number DSM ACC3092 (monoclonal antibody LG96) or DSM ACC3093 (monoclonal antibody MG97). The analyte is a Z-AAT protein, present in the sample from a PiZ gene carrier.EFFECT: use of the group of inventions improves the efficiency of determining presence of an analyte, particularly a Z-AAT protein.25 cl, 33 dwg, 1 tbl, 5 ex |
