发明名称 CRYSTALLINE FORM OF 2-CHLORO-4-METHOXY-N-[4-(8-METHYL-IMIDAZO[1,2-a]PYRIDIN-2-YL)-PHENYL]-BENZAMIDE, ACTIVE COMPONENT, PHARMACEUTICAL COMPOSITION AND MEDICINAL AGENT
摘要 FIELD: chemistry.SUBSTANCE: invention relates to a crystalline form of 2-chloro-4-methoxy-N-[4-(8-methyl-imidazo[1,2-a]pyridin-2-yl)-phenyl]-benzamide of formula 1. The invention also relates to a pharmaceutical composition and a medicinal agent based on a compound of formula 1, which can be used to prevent and treat a proliferative disease associated with the triggering of Hedgehog (Hh) embryonic signalling cascade.EFFECT: obtaining a crystalline form of a compound of formula 1, characterised by high rate of dissolution and high storage stability.6 cl, 1 dwg, 2 tbl, 5 ex
申请公布号 RU2569305(C1) 申请公布日期 2015.11.20
申请号 RU20140145116 申请日期 2014.11.10
申请人 FEDERAL'NOE GOSUDARSTVENNOE AVTONOMNOE OBRAZOVATEL'NOE UCHREZHDENIE VYSSHEGO PROFESSIONAL'NOGO OBRAZOVANIJA "MOSKOVSKIJ FIZIKO-TEKHNICHESKIJ INSTITUT(GOSUDARSTVENNYJ UNIVERSITET)" (MFTI) 发明人 LEONOV SERGEJ VIKTOROVICH;MARUSICH ELENA IVANOVNA
分类号 C07D471/04;A61K31/437;A61P35/00 主分类号 C07D471/04
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