| 发明名称 |
POLYMERIC PARTICLES-BASED TEMOZOLOMIDE DOSAGE FORM |
| 摘要 |
The invention relates to pharmacology and medicine, and more specifically to slow-release antitumor drug composition based on biodegradable poly(lactic-co-glycolic acid) (PLGA). The composition comprises temozolomide (TMZ) as the active ingredient and comprises, in addition, surface-active material and a cryoprotectant as parts of nanoparticles. |
| 申请公布号 |
US2015328169(A1) |
申请公布日期 |
2015.11.19 |
| 申请号 |
US201314650799 |
申请日期 |
2013.12.10 |
| 申请人 |
OY FILANA LTD ;UNICHEMPHARM LTD |
发明人 |
VASILENKO Ekaterina;VORONTSOV Evgeny;SEVERIN Evgenij;GULENKO Victor;MITROKHIN Maxim;IURCHENKO Maksim |
| 分类号 |
A61K9/51;A61K31/495 |
主分类号 |
A61K9/51 |
| 代理机构 |
|
代理人 |
|
| 主权项 |
1. A pharmaceutical composition comprising temozolomide, a biodegradable polymer, a surface-active material and a cryoprotectant, with the following component ratios, % wt:temozolomide10-20biodegradable polymer65-80surface-active material2-3cryoprotectantup to 100% wt,as parts of nanoparticles. |
| 地址 |
Aura FI |
