发明名称 New crystal form VII of agomelatine, preparation method and use thereof and pharmaceutical composition containing same
摘要 The present invention provides a new crystal form VII of agomelatine, the preparation method and use thereof and a pharmaceutical composition containing the same. The new crystal form has a good purity, a stable crystal form and good reproducibility; the preparation method thereof is easy to amplify; and it is superior to most previously reported crystal forms in terms of stability and solubility. Therefore, the crystal form VII of the present invention has an advantage in terms of preparation.
申请公布号 AU2012231547(B2) 申请公布日期 2015.11.19
申请号 AU20120231547 申请日期 2012.03.22
申请人 LES LABORATOIRES SERVIER;SHANGHAI INSTITUTE OF PHARMACEUTICAL INDUSTRY 发明人 HUANG, YU;TONG, LING;ZHU, XUEYAN;SHAN, HANBIN;YUAN, ZHEDONG;YU, XIONG
分类号 C07C233/18;A61K31/165;A61P1/00;A61P9/00;A61P25/00;A61P25/20;A61P25/22;A61P25/24;C07C231/24 主分类号 C07C233/18
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