发明名称 ENZYME DELIVERY SYSTEM AND METHOD OF PREPARATION AND USE
摘要 PROBLEM TO BE SOLVED: To provide a pharmaceutical composition containing an enzyme preparation containing an enzyme which is effective in the treatment of autism, ADD, ADHD, Parkinson's disease, cystic fibrosis, or other behavioral disorders in neurological conditions, which is sensitive to the treatment by pancreatic enzyme or a digestive enzyme, and to provide a method for preparing and using the preparations.SOLUTION: The invention provides: an encapsulated digestive enzyme preparation which contains a core containing enzyme particles in which an enzyme is present in the amount of about 5-95% by weight, and an emulsifiable lipid by exposure to a solvent, the core being continuously coated with the lipid; a pharmaceutical composition containing the enzyme preparation; and a method for using the preparation. The method comprises a step of providing the enzyme particles, a step of blending the emulsifiable lipid with additives to obtain a lipid blend, and a step of preparation of the encapsulated enzyme preparation by coating the digestive enzyme particles with the lipid blend.
申请公布号 JP2015205892(A) 申请公布日期 2015.11.19
申请号 JP20150109335 申请日期 2015.05.29
申请人 CUREMARK LLC 发明人 JOAN M FALLON;MATTHEW HEIL
分类号 A61K38/46;A61K9/02;A61K9/10;A61K9/107;A61K9/127;A61K9/14;A61K9/16;A61K9/20;A61K9/46;A61K9/48;A61K9/70;A61K47/12;A61K47/14;A61K47/24;A61K47/34;A61K47/44;A61P1/00;A61P3/00;A61P25/00;A61P25/14;A61P25/16;A61P43/00 主分类号 A61K38/46
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