发明名称 |
SYDNONE DERIVATIVES FOR CONJUGATION OF COMPOUNDS OF INTEREST |
摘要 |
The present invention relates to a process for the preparation of a first compound of interest C1 functionalized with a sydnone compound and to the corresponding functionalized C1 compound of interest. The present invention also relates to a process for the preparation of a conjugate of two compounds of interest C1 and C2 implying a sydnone compound and to the obtained conjugate. The present invention also relates to a process for preparing a compound of interest C2 comprising a strained alkyne moiety functionalized with a sydnone and to the corresponding functionalized compound of interest C2. It also relates to novel sydnone compounds substituted in position 4, which may be used in the above processes. |
申请公布号 |
WO2015173419(A1) |
申请公布日期 |
2015.11.19 |
申请号 |
WO2015EP60805 |
申请日期 |
2015.05.15 |
申请人 |
UNIVERSITE DE STRASBOURG;CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE;COMMISSARIAT A L'ENERGIE ATOMIQUE ET AUX ENERGIESALTERNATIVES |
发明人 |
TARAN, FRÉDÉRIC;WAGNER, ALAIN;KOLODYCH, SERGII;KONIEV, OLEKSANDR |
分类号 |
A61K47/48;A61K49/00;C07D271/04 |
主分类号 |
A61K47/48 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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