发明名称 |
METHODS AND COMPOSITIONS FOR TREATING AUTOIMMUNE AND INFLAMMATORY CONDITIONS |
摘要 |
Described herein are compositions and methods for inhibiting an inflammatory or autoimmune response and for inducing immune tolerance in a subject in need thereof comprising administering to the subject a therapeutically effective amount of an antigen presenting cell (APC)-targeted antibody operatively linked to IL-10 or a fragment thereof. The compositions and methods described herein are useful for treating inflammatory and autoimmune disorders. |
申请公布号 |
CA2949081(A1) |
申请公布日期 |
2015.11.19 |
申请号 |
CA20152949081 |
申请日期 |
2015.05.15 |
申请人 |
BAYLOR RESEARCH INSTITUTE |
发明人 |
OH, SANGKON;ZURAWSKI, SANDRA;JOO, HYEMEE;ZURAWSKI, GERARD |
分类号 |
A61K39/00;A01N63/00;A61K38/20;A61K39/395;A61P19/02;A61P29/00;C07K19/00 |
主分类号 |
A61K39/00 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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