发明名称 Stilbenoid Derivatives And Their Uses
摘要 The present invention generally provides stilbenoid derivatives and methods for using stilbenoid derivatives to modulate the activity of cannabinoid receptors or scavenge reactive nitrogen species.
申请公布号 US2015328243(A1) 申请公布日期 2015.11.19
申请号 US201514721551 申请日期 2015.05.26
申请人 ARKANSAS STATE UNIVERSITY 发明人 Radominska-Pandya Anna;Prather Paul L.;Medina-Bolivar Luis Fabricio;Mayeux Philip R.
分类号 A61K31/7034 主分类号 A61K31/7034
代理机构 代理人
主权项 1. A method for modulating activity of a cannabinoid receptor, the method comprising contacting the cannabinoid receptor with a monomer or an oligomer of a compound comprising Formula (I) such that the activity of the cannabinoid receptor is modulated; the compound comprising Formula (I): wherein: R1, R2, R3, R4, R5, R6, R7, R8, R9, and R10 are independently chosen from hydrogen, hydroxyl, hydrocarbyl, substituted hydrocarbyl, hydrocarbyloxy, substituted hydrocarbyloxy, and sulfoxy; provided that at least one of the R groups is a hydroxyl or substituted hydroxyl group; and provided that if the compound comprising Formula (I) is monomeric, then the compound comprising Formula (I) is other than resveratrol.
地址 STATE UNIVERSITY AR US