发明名称 PREVENTIVE OR THERAPEUTIC AGENT FOR PAIN ASSOCIATED WITH HERPES ZOSTER IN ACUTE PHASE
摘要 A P2X4 receptor antagonist such as paroxetine, a diazepinedione derivative having the following formula (IX) is used as an agent for preventing or treating zoster-associated pain in acute phase:;;wherein R1 is hydrogen, a C1-8 alkyl group, or the like; each of R2 and R3 is hydrogen, a C1-8 alkyl group, or the like;each of R4 and R5 is hydrogen or the like; andW is a five-membered or six-membered heterocyclic ring optionally having one or more substituents and comprising one to four nitrogen atoms as the members of the ring.
申请公布号 US2015328231(A1) 申请公布日期 2015.11.19
申请号 US201514808609 申请日期 2015.07.24
申请人 KYUSHU UNIVERSITY ;NIPPON CHEMIPHAR CO., LTD. 发明人 INOUE Kazuhide;TSUDA Makoto;MATSUMURA Yuta
分类号 A61K31/5513 主分类号 A61K31/5513
代理机构 代理人
主权项 1. (canceled)
地址 Fukuoka-shi JP