| 发明名称 |
METHODS AND COMPOSITIONS USING FGF-9 TO ENHANCE NEOVASCULARIZATION AND REGENERATION |
| 摘要 |
In an aspect, the invention relates to compositions and methods of enhancing neovascularization. In an aspect, the invention relates to compositions and methods for attenuating vascular apoptosis. In an aspect, the invention relates to compositions and methods for inhibiting vascular apoptosis. This abstract is intended as a scanning tool for purposes of searching in the particular art and is not intended to be limiting of the present invention. |
| 申请公布号 |
US2015328285(A1) |
申请公布日期 |
2015.11.19 |
| 申请号 |
US201314389408 |
申请日期 |
2013.03.09 |
| 申请人 |
UNIVERSITY OF CENTRAL FLORIDA RESEARCH FOUNDATION, INC. |
发明人 |
Singla Dinendar |
| 分类号 |
A61K38/18;A61K35/545;A61K38/13;A61K45/06 |
主分类号 |
A61K38/18 |
| 代理机构 |
|
代理人 |
|
| 主权项 |
1. A method of enhancing neovascularization following cardiac dysfunction in a subject in need thereof, the method comprising:
administering to the subject (i) fibroblast growth factor-9 primed induced pluripotent stem cells; (ii) conditioned medium of fibroblast growth factor-9 primed induced pluripotent stem cells; (iii) fibroblast growth factor-9; (iv) a composition comprising fibroblast growth factor-9 and fibroblast growth factor-8; or (vi) a combination thereof, and determining neovascularization in the heart. |
| 地址 |
Orlando FL US |
