发明名称 RAPID-ACTING INSULIN FORMULATION COMPRISING A SUBSTITUTED ANIONIC COMPOUND AND A POLYANIONIC COMPOUND
摘要 <p>The invention relates to a composition in aqueous solution comprising insulin in hexameric form, at least one substituted anionic compound and at least one polyanionic compound, said substituted anionic compound being formed by a discrete number n, between 1 and 8, of identical or different saccharide unit(s), linked by identical or different glycosidic bonds, said saccharide unit or one of said saccharide units taking the oxidised or reduced open form, said compound comprising salifiable carboxyl groups and said substituted anionic compound bearing at its reducing chain end at least one AA radical originating from an aromatic amino acid comprising a phenyl or an indole, optionally substituted, or from a derivative of aromatic amino acid comprising a phenyl or an indole, optionally substituted.</p>
申请公布号 WO2015173373(A1) 申请公布日期 2015.11.19
申请号 WO2015EP60716 申请日期 2015.05.14
申请人 ADOCIA 发明人 SOULA, OLIVIER;CHARVET, RICHARD;MORA, GUILHEM
分类号 A61K38/28;A61K47/36;C07H7/04 主分类号 A61K38/28
代理机构 代理人
主权项
地址