发明名称 |
TREATMENT OF LUNG CANCER USING A COMBINATION OF AN ANTI-PD-1 ANTIBODY AND ANOTHER ANTI-CANCER AGENT |
摘要 |
This disclosure provides a method for treating a subject afflicted with a lung cancer, which method comprises administering to the subject therapeutically effective amounts of: (a) an anti-cancer agent which is an antibody or an antigen-binding portion thereof that specifically binds to a Programmed Death-1 (PD-1) receptor and inhibits PD-1 activity; and (b) another anti-cancer agent. The other anti-cancer agent can be a platinum-based doublet chemotherapy, an EGFR-targeted tyrosine kinase inhibitor, bevacizumab, an anti- Cytotoxic T-Lymphocyte Antigen-4 (CTLA-4) antibody, or any other therapy used to treat lung cancer in the art or disclosed herein. |
申请公布号 |
CA2949121(A1) |
申请公布日期 |
2015.11.19 |
申请号 |
CA20152949121 |
申请日期 |
2015.05.15 |
申请人 |
BRISTOL-MYERS SQUIBB COMPANY |
发明人 |
FELTQUATE, DAVID;CHEN, ALLEN C. |
分类号 |
A61K39/395;A61P35/00;C07K16/22;C07K16/28;C07K16/30 |
主分类号 |
A61K39/395 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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