发明名称 球状の無水リン酸水素カルシウムを用いた崩壊性に優れた錠剤、および球状の無水リン酸水素カルシウムを賦形剤として用いた崩壊性に優れた錠剤
摘要 PROBLEM TO BE SOLVED: To provide a small-sized tablet useful as a calcium supplement which has not only properties such as moldability in preparing the tablet and hardness required for the tablet, but also excellent disintegrability in taking, and a tablet using the anhydrous calcium hydrogen phosphate as a filler.SOLUTION: There is provided a tablet which contains: (a) spherical anhydrous calcium hydrogen phosphate having an average particle diameter of 50 to 100 μm, and BET specific surface area of 5 to 30 m/g; and (b) crospovidone having an average particle diameter of 20 to 40 μm, which is a tablet in which the (a) component is 65.0 to 98.0% and the (b) component is 1.5 to 5.0% based on the total weight of the tablet as a reference, tensile strength is 1.2 to 2.2 MPa, and average disintegration time is 2 to 7 seconds.
申请公布号 JP2015205852(A) 申请公布日期 2015.11.19
申请号 JP20140088623 申请日期 2014.04.22
申请人 发明人
分类号 A61K33/06;A61K9/20;A61K47/04;A61K47/32;A61P19/10 主分类号 A61K33/06
代理机构 代理人
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