The present invention provides methods and materials relating to obtaining or expanding populations of islet cells, and uses of the islet cells obtained by these methods, for example in the treatment of diabetes. The invention uses transcription factors in a process of expansion and de-differention, followed by redifferentiation.
申请公布号
WO2015173578(A1)
申请公布日期
2015.11.19
申请号
WO2015GB51430
申请日期
2015.05.14
申请人
THE UNIVERSITY COURT OF THE UNIVERSITY OF ABERDEEN;LOTHIAN HEALTH BOARD
发明人
DOCHERTY, KEVIN;DOCHERTY, HILARY, MARGARET;MARQUES DE LIMA, MARIA, JOAO;MUIR, KENNETH, ROSS;CASEY, JOHN, JOSEPH