发明名称 |
IMIDAZOPYRAZINE Syk INHIBITOR |
摘要 |
PROBLEM TO BE SOLVED: To provide an imidazopyrazine Syk inhibitor.SOLUTION: A certain specific imidazopyrazine and pharmaceutical composition thereof are provided in this specification. There is provided a method of treating patients with specific disease and disorder responding to inhibition of Syk activity, including a step of administering at least one kind of chemical substance with an efficient amount for reducing evidence or symptom of the disease or disorder to the patients. There is also provided a method for determining the presence or absence of a Syk kinase in samples. |
申请公布号 |
JP2015205935(A) |
申请公布日期 |
2015.11.19 |
申请号 |
JP20150159313 |
申请日期 |
2015.08.12 |
申请人 |
GILEAD CONNECTICUT INC |
发明人 |
SCOTT A MITCHELL;KEVIN S CURRIE;PETER A BLOMGREN;JEFFREY E KROPF;LEE SEUNG H;XU JIANJUN;DOUGLAS G STAFFORD;JAMES P HARDING;ANTONIO J BARBOSA JR;ZHAO ZHONGDONG;DAVID M ARMISTEAD |
分类号 |
C07D487/04;A61K31/4985;A61K31/506;A61K31/517;A61K31/5377;A61K31/538;A61K31/5383;A61K31/541;A61K31/553;A61P11/00;A61P11/02;A61P13/12;A61P25/00;A61P29/00;A61P35/00;A61P35/02;A61P37/06;A61P37/08;A61P43/00;C07D519/00;C12N5/0781;C12N9/99;C12Q1/02;C12Q1/48;C12Q1/68 |
主分类号 |
C07D487/04 |
代理机构 |
|
代理人 |
|
主权项 |
|
地址 |
|