发明名称 MR IMAGING DIAGNOSTIC AGENT FOR INTRACTABLE NEUROLOGICAL DISEASE
摘要 Disclosed is a compound represented by formula (1) or a salt thereof, formula (1) : wherein X is a residue of a compound having activity of binding to at least one member selected from the group consisting of amyloid ² proteins, tau proteins, ±-synuclein, and TDP-43; m is an integer of 0 to 6; n is an integer of 1 to 5; and J is a group selected from the group consisting of wherein R 1 and R 2 are each independently a hydrogen atom, a fluorine atom, methyl, or trifluoromethyl; R 3 is trifluoromethyl or trifluoromethoxy; and p is an integer of 1 to 4, provided that m + n ‰¥ 5 when J is J-1, and m + n ‰¥ 7 when J is J-2 or J-3.
申请公布号 EP2944626(A1) 申请公布日期 2015.11.18
申请号 EP20140737825 申请日期 2014.01.06
申请人 SHIGA UNIVERSITY OF MEDICAL SCIENCE 发明人 TOOYAMA, IKUO;TAGUCHI, HIROYASU;YANAGISAWA, DAIJIRO
分类号 A61K49/12;A61P25/28;C07C235/34;C07D263/56 主分类号 A61K49/12
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