发明名称 |
HIGH EFFICIENCY METHOD FOR PURIFYING HUMAN PAPILLOMAVIRUS VIRUS-LIKE PARTICLES. |
摘要 |
The present invention relates to a method for purifying a human papillomavirus (HPV) L1 protein to a high level of purity at high efficiency. According to the purification method of the present invention, the purification purity and yield of an HPV L1 protein can be remarkably improved in the case where cell lysate is treated with a reducing agent and annealed. Also, HPV L1 virus-like particles which are purified by the purification method of the present invention exhibit excellent antigenicity and immunogenicity. |
申请公布号 |
MX2015001413(A) |
申请公布日期 |
2015.11.18 |
申请号 |
MX20150001413 |
申请日期 |
2013.07.30 |
申请人 |
HONG-JIN KIM |
发明人 |
KIM, HONG-JIN;KIM, HYOUNG JIN |
分类号 |
C07K1/16;C07K14/025 |
主分类号 |
C07K1/16 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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