发明名称 NANOMETERSIZED METAL SALEN COMPLEX COMPOUNDS, THEIR PREPARATION AND THEIR USE AS SYSTEMIC ANTITUMOR AGENTS
摘要 <p>The present invention provides a metal-salen complex compound of the formula shown below having a controlled grain size that enables the metal-salen complex compound to exert its pharmacological effects as anticancer drug, at a target region, when guided by magnetic fields to the affected tissue. This metal-salen complex compound has a crystal grain size of 8 µm or less, and that is represented by the chemical formula below. N,N'-Bis(salicylidene)ethylenediamine metal M is Fe, Cr, Mn, Co, Ni, Mo, Ru, Rh, Pd, W, Re, Os, Ir, Pt, Nd, Sm, Eu, or Gd.</p>
申请公布号 EP2944627(A1) 申请公布日期 2015.11.18
申请号 EP20150168720 申请日期 2011.12.21
申请人 IHI CORPORATION;ISHIKAWA, YOSHIHIRO 发明人 ISHIKAWA, YOSHIHIRO;EGUCHI, HARUKI
分类号 C07C251/24;A61K9/00;A61K9/50;A61K31/28;A61K31/555;A61P35/00;C07F15/02 主分类号 C07C251/24
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