| 发明名称 |
ENA nucleic acid drugs modifying splicing in mRNA precursor |
| 摘要 |
<p>Oligonucleotides having a nucleotide sequence complementary to nucleotide numbers such as 2571-2607, 2578-2592, 2571-2592, 2573-2592, 2578-2596, 2578-2601 or 2575-2592 of the dystrophin cDNA (Gene Bank accession No. NM_004006.1) and therapeutic agents for muscular dystrophy comprising such oligonucleotides. <IMAGE></p> |
| 申请公布号 |
EP2530156(B1) |
申请公布日期 |
2015.11.18 |
| 申请号 |
EP20120182258 |
申请日期 |
2003.11.21 |
| 申请人 |
MATSUO, MASAFUMI;ORPHAN DISEASE TREATMENT INSTITUTE CO., LTD.;TAKESHIMA, YASUHIRO;DAIICHI SANKYO COMPANY, LIMITED |
发明人 |
MATSUO, MASAFUMI;TAKESHIMA, YASUHIRO;KOIZUMI, MAKOTO |
| 分类号 |
A61K31/7088;A61K31/712;A61K31/7125;A61K38/00;A61K48/00;A61P21/04;C07H21/04;C12N15/113 |
主分类号 |
A61K31/7088 |
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