Containers for compositions comprising meloxicam

摘要

A plastic container containing a pharmaceutical composition comprising benzoic acid or a derivative or a pharmaceutically acceptable salt thereof and a COX-inhibitor of the oxicam-type or a pharmaceutical acceptable salt thereof, wherein the container material selected from one or more members of the group consisting of a homopolymer of polypropylene (PP), a copolymer of polypropylene (PP), a homopolymer of polyethylene terephthalate (PET) and a copolymer of polyethylene terephthalate (PET), and optionally one or more non-polymeric components.

主权项

1. A pharmaceutically acceptable container containing a pharmaceutical composition including sodium benzoate, the container being formed of a container material selected from one or more members of the group constisting of a homopolymer of polypropylene (PP), a copolymer of polypropylene (PP), a homopolymer of polyethylene terephthalate (PET) and a copolymer of polyethylene terephthalate (PET);
wherein the container material does not include high-density polyethylene (HDPE), low-densisty polyethylene (LDPE), or polycarbonate (PC); and a loss in concentration (mg/mL) of sodium benzoate in said pharmaceutical composition due to adsorption onto said container when stored for a period of 6 months at 25° C. and a relative humidity of 60% is no more than 5%.