Method for improving acid tolerance of <i>Propionibacterium acidipropionici </i>

摘要

The invention provides a simple and effective method for improving acid tolerance of P. acidipropionici by adding arginine and/or aspartic acid to the culture medium. The acid tolerance of P. acidipropionici was improved by 60% and 20% respectively through adding arginine or aspartic acid into the culture medium. Consequently, PA production was improved by 36% and 26%, respectively. The maximal PA production was obtained by adding both 20 mM arginine and 20 mM aspartic acid. This method can be applied to large scale production of PA.

主权项

1. A method for improving acid tolerance of P. acidipropionici comprises adding arginine into a culture medium during culturing said P. acidipropionici.