发明名称 Treatment of osteoarthritis pain
摘要 This invention discloses a method of treatment of osteoarthritis pain by administration of a histamine H3 receptor antagonist, described herein, a salt thereof, or a composition comprising such compound or salt.
申请公布号 US9186353(B2) 申请公布日期 2015.11.17
申请号 US201012767608 申请日期 2010.04.26
申请人 AbbVie Inc. 发明人 Cowart Marlon D.;Hsieh Gin C.;Brioni Jorge D.;Sullivan James P.
分类号 A61K31/55;A61K31/425;A61K31/454;A61K31/501;A61K31/551;A61K31/517;A61K31/4375;A61K31/40;A61K31/497;A61K31/445;A61K31/428;A61K31/395;A61K31/41 主分类号 A61K31/55
代理机构 Michael Best & Friedrich LLP 代理人 Mueller Lisa V.;Michael Best & Friedrich LLP
主权项 1. A method of treatment of osteoarthritis pain comprising administration of a histamine H3 receptor antagonist, a salt thereof, or a composition comprising such histamine H3 receptor antagonist or salt, to a mammal in need of treatment thereof, wherein the histamine H3 receptor antagonist is 2-[4-((1S,2S)-2-{[(2S)-2-methylpyrrolidin-1-yl]methyl}cyclopropyl)phenyl]pyridazin-3(2H) one.
地址 North Chicago IL US