发明名称 |
Treatment of osteoarthritis pain |
摘要 |
This invention discloses a method of treatment of osteoarthritis pain by administration of a histamine H3 receptor antagonist, described herein, a salt thereof, or a composition comprising such compound or salt. |
申请公布号 |
US9186353(B2) |
申请公布日期 |
2015.11.17 |
申请号 |
US201012767608 |
申请日期 |
2010.04.26 |
申请人 |
AbbVie Inc. |
发明人 |
Cowart Marlon D.;Hsieh Gin C.;Brioni Jorge D.;Sullivan James P. |
分类号 |
A61K31/55;A61K31/425;A61K31/454;A61K31/501;A61K31/551;A61K31/517;A61K31/4375;A61K31/40;A61K31/497;A61K31/445;A61K31/428;A61K31/395;A61K31/41 |
主分类号 |
A61K31/55 |
代理机构 |
Michael Best & Friedrich LLP |
代理人 |
Mueller Lisa V.;Michael Best & Friedrich LLP |
主权项 |
1. A method of treatment of osteoarthritis pain comprising administration of a histamine H3 receptor antagonist, a salt thereof, or a composition comprising such histamine H3 receptor antagonist or salt, to a mammal in need of treatment thereof, wherein the histamine H3 receptor antagonist is 2-[4-((1S,2S)-2-{[(2S)-2-methylpyrrolidin-1-yl]methyl}cyclopropyl)phenyl]pyridazin-3(2H) one. |
地址 |
North Chicago IL US |