发明名称 キナーゼ阻害剤としてのイミダゾ[1,2−b]ピリダジン誘導体
摘要 <p>The present invention is intended to provide a compound or a pharmacologically acceptable salt thereof which is useful in the treatment of a tumor through its ROS1 kinase enzyme activity inhibitory effect and NTRK kinase enzyme inhibitory effect. The present invention provides a compound having an imidazo[1,2-b]pyridazine structure represented by the general formula (I) or a pharmacologically acceptable salt thereof, and a pharmaceutical composition comprising the compound. In the formula, R 1 , G, T, Y 1 , Y 2 , Y 3 , and Y 4 are as defined herein.</p>
申请公布号 JP5814467(B2) 申请公布日期 2015.11.17
申请号 JP20140519977 申请日期 2013.06.03
申请人 第一三共株式会社 发明人 武田 泰幸;吉川 謙次;神子島 佳子;山本 裕子;田中 亮一;冨永 裕一;木我 真基;浜田 義人
分类号 C07D487/04;A61K31/5025;A61P35/00;A61P35/02;A61P43/00 主分类号 C07D487/04
代理机构 代理人
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