主权项 |
1. A compound selected from the group consisting of:
i. 2-(4-Hydroxy-3-propoxy-phenyl)-chroman-3,5,7-triol; ii. 2-(3-Hydroxy-4-propoxy-phenyl)-chroman-3,5,7-triol; iii. 2-(3-ethoxy-4-Hydroxy-phenyl)-chroman-3,5,7-triol; iv. 2-(4-ethoxy-3-Hydroxy-phenyl)-chroman-3,5,7-triol; v. 2-(3,4-Dihydroxy-phenyl)-3-propoxy-chroman-5,7-diol; vi. methyl 4-((2R,3R)-3-hydroxy-5,7-dimethoxychroman-2-yl)-2-methoxybenzoate; vii. methyl 5-((2R,3R)-3-hydroxy-5,7-dimethoxychroman-2-yl)-2-methoxybenzoate; viii. (4-((2R,3R)-3-hydroxy-5,7-dimethoxychroman-2-yl)-2-methoxyphenyl)(4-methylpiperazin-1-yl)methanone; ix. ethyl 2-(4-((2R,3R)-3-hydroxy-5,7-dimethoxychroman-2-yl)-2-methoxyphenoxy)acetate; x. ethyl 2-(5-((2R,3R)-3-hydroxy-5,7-dimethoxychroman-2-yl)-2-methoxyphenoxy)acetate; xi. 2-(4-((2R,3R)-3-hydroxy-5,7-dimethoxychroman-2-yl)-2-methoxyphenoxy) acetic acid; xii. ethyl 2-(2-hydroxy-4-((2R,3R)-3,5,7-dimethoxychroman-2-yl)phenoxy)acetate; xiii. ethyl 2-(2-hydroxy-5-((2R,3R)-3,5,7-dimethoxychroman-2-yl)phenoxy)acetate; xiv. (2R,3R)-2-(3,4-dihydroxyphenyl)-3-methoxychroman-5,7-diol; xv. (2R,3R)-2-(3,4-dihydroxyphenyl)-5,7-dihydroxychroman-3-yl acetate; xvi. 1-(((2R,3R)-2-(3,4-dihydroxyphenyl)-5,7-dihydroxychroman-3-yl)oxy)ethyl isobutyrate; xvii. (((2R,3R)-2-(3,4-dihydroxyphenyl)-5,7-dihydroxychroman-3-yl)oxy)methyl diisopropylcarbamate; xviii. tert-butyl ((((2R,3R)-2-(3,4-dihydroxyphenyl)-5,7-dihydroxychroman-3-yl)oxy)methyl)carbonate; xix. 4-((2R,3R)-3,5,7-trihydroxychroman-2-yl)-1,2-phenylene dioctanoate; xx. (2R,3R)-2-(3,4-dihydroxyphenyl)-5,7-dihydroxychroman-3-yl octanoate; xxi. (2R,3R)-2-(3,4-diacetoxyphenyl)chroman-3,5,7-triyl triacetate; xxii. 4-((2R,3R)-3,5,7-trihydroxychroman-2-yl)-1 phenylene diacetate; xxiii. 4-((2R,3R)-3,5,7-trihydroxychroman-2-yl)-1,2-phenylene diacetate; xxiv. (2R,3R)-2-(3,4-dihydroxyphenyl)-3-methylchroman-3,5,7-triol; and xxv. a racemic mixture or a pharmaceutically acceptable salt thereof of any of (i) to (xxiv). |