| 发明名称 | Poly (ADP-ribose) polymerase inhibitor | ||
| 摘要 | Disclosed are a phthalic hydrazide (phthalazine ketone) compound, and a pharmaceutical composition comprising the same. As a DNA repair enzyme poly (ADP-ribozyme) polymerase inhibitor, the compound and the pharmaceutical composition can effectively treat diseases involving PARP enzymatic activity, including cancer, neural degenerative diseases, inflammation and the like. | ||
| 申请公布号 | US9187430(B2) | 申请公布日期 | 2015.11.17 |
| 申请号 | US201214361698 | 申请日期 | 2012.12.03 |
| 申请人 | CHENGDU DI'AO PHARMACEUTICAL GROUP CO., LTD. | 发明人 | Ji Jianxin;Guo Na;Xue Ting;Kang Bingqiang;Ye Xinfa;Chen Xin;Zhang Tao |
| 分类号 | C07D237/32;C07D401/14;C07D413/14;A61K31/502;A61K31/5025;C07D401/12;C07D407/14;C07D409/14;C07D417/14 | 主分类号 | C07D237/32 |
| 代理机构 | Jun He Law Offices P.C. | 代理人 | Jun He Law Offices P.C. ;Zhu James J. |
| 主权项 | 1. The compound 4-(3-(4-(1-(dimethylamino)cyclopropanecarbonyl) piperazine-1-carbonyl)-4-fluorophenoxy)2H-phthalazin-1-one, pharmaceutically acceptable salt or stereoisomer thereof. | ||
| 地址 | High-Tech Devlopment Zone, Chengdu CN | ||