Hair follicle targeting compositions

摘要

This invention provides topical pharmaceutical or cosmetic compositions, and uses thereof in treating a disease or condition of the hair follicle. The compositions of this invention are emulsions of an oil-in-polyol with a mean particle size of below one micron, and further comprising at least one oil, one polyol, and one stabilizer.

主权项

1. A method of targeting a bio-active agent in hair follicles, comprising:
topically applying to skin and hair follicles until well absorbed a cream composition of oil-in-polyol emulsion having a mean particle size of 200 to 2000 nanometers, containing (a) a dissolved bio-active agent selected from the group consisting of a depilatory, a coloring agent that facilitates laser photothermolysis, a coloring agent applied for cosmetic hair coloring, an anti-inflammatory agent, a hair growing agent, an antibiotic for propionibacterium acne, a retinoid, an anti-fungal agent, and an immune-modulator, (b) an oil, (c) from about 60 to about 90% by weight of a polyol, and (d) a stabilizer; wherein said bio-active agent is dissolved in the oil base of said emulsion, and accumulated within hair follicles.