Feedback systems and methods utilizing two or more sites along denervation catheter

摘要

A renal denervation system includes a renal denervation catheter and a flow determining system. The renal denervation catheter includes a plurality of ablation members positioned at a distal end portion thereof. The renal denervation catheter is insertable into a renal artery. The flow determining system includes a processor and first and second flow determining members spaced apart on the renal denervation catheter. The processor is configured to determine a change in blood flow through the renal artery resulting from a renal denervation procedure using the renal denervation catheter in response to input from the first and second flow determining members.

主权项

1. A renal denervation system, comprising:
a renal denervation catheter having a plurality of ablation members positioned at a distal end portion thereof and being insertable into a renal artery; a flow determining system selected from the group consisting of:
a first flow determining member comprising at least one fluid port configured to release a flow of fluid into the renal artery, a second flow determining member comprising at least one sensor configured to detect the flow of the fluid, and a processor configured to determine a time delay between releasing the flow of fluid and detecting the flow of fluid prior to and after treating the renal artery with the renal denervation catheter;a first flow determining member and a second flow determining member being spaced apart along a length of the renal denervation catheter each comprising at least one pressure sensor configured to measure a pressure wave advanced through the renal artery in a first direction and reflected through the renal artery in an opposite direction, and a processor configured to determine a change in amplitude of the pressure wave reflected through the renal artery; anda first flow determining member and a second flow determining member each comprising at least one wire coil, the first flow determining member configured to generate an electromagnetic field to orient dipoles of red blood cells in the blood flow passing through the at least one wire coil of the first flow determining member, the red blood cells inducing current in the at least one wire coil of the second flow determining member, and a processor configured to determine a change in blood flow through the renal artery resulting from a renal denervation procedure using the renal denervation catheter and in response to input from the first and second flow determining members.