Crystalline forms of tenofovir dipivoxil fumarate

摘要

The present invention relates to a crystalline form of tenofovir dipivoxil fumarate, a crystalline composition and a pharmaceutical composition comprising the crystalline form, and also to a process for preparing the same and the use for prophylaxis or treatment of a disease associated with a viral infection. The crystalline form has an X-ray powder diffraction pattern using Cu-Kα radiation, expressed in terms of lattice spacing “d” comprising peaks at about 18.4714 Å, 5.0350 Å, 4.6380 Å, 4.5347 Å, 4.3838 Å, 4.2874 Å and 3.6304 Å.

主权项

1. A crystalline form of tenofovir dipivoxil fumarate, having an X-ray powder diffraction pattern using Cu-Kα radiation, expressed in terms of lattice spacing “d” comprising peaks at 18.4714Å, 5.0350Å, 4.6380Å, 4.5347Å, 4.3838Å, 4.2874Å and 3.6304 Å.