发明名称 |
METHODS FOR PREPARATION OF CYTOTOXIC CONJUGATES OF MAYTANSINOIDS AND CELL BINDING AGENTS |
摘要 |
<p>The Invention provides a method for producing a cytotoxic conjugate which comprises one or more maytansinoid molecules and a cell binding agent, said method consisting essentially of the single step of reacting one or more maytansinoid molecules containing a reactive ester with a cell binding agent.</p> |
申请公布号 |
PT2348024(E) |
申请公布日期 |
2015.11.13 |
申请号 |
PT20020003908T |
申请日期 |
2002.02.14 |
申请人 |
IMMUNOGEN, INC. |
发明人 |
WAYNE C. WIDDISON;RAVI V.J. CHARI |
分类号 |
C07D491/12;A61K31/537;A61K47/48;A61P35/00;A61P35/02;C07D498/18 |
主分类号 |
C07D491/12 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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