| 发明名称 |
QUANTITATION OF TAMOXIFEN AND METABOLITES THEREOF BY MASS SPECTROMETRY |
| 摘要 |
Provided are methods for determining the amount of tamoxifen and its metabolites in a sample by mass spectrometry. In some aspects, the methods provided herein comprise determining the amount of norendoxifen. In some aspects, the methods provided herein comprise determining the amount of norendoxifen and tamoxifen. In some aspects, the methods provided herein comprise determining the amount of norendoxifen and other tamoxifen metabolites. In some aspects, the methods provided herein comprise determining the amount of tamoxifen, norendoxifen, and other tamoxifen metabolites. |
| 申请公布号 |
US2015323513(A1) |
申请公布日期 |
2015.11.12 |
| 申请号 |
US201514710311 |
申请日期 |
2015.05.12 |
| 申请人 |
QUEST DIAGNOSTICS INVESTMENTS INCORPORATED |
发明人 |
CLARKE Nigel |
| 分类号 |
G01N33/15;H01J49/00 |
主分类号 |
G01N33/15 |
| 代理机构 |
|
代理人 |
|
| 主权项 |
1. A method for determining the amount of norendoxifen in a sample by mass spectrometry, comprising:
(a) ionizing said norendoxifen to produce one or more norendoxifen ions detectable by mass spectrometry; (b) detecting the amount of the norendoxifen ion(s) from step by mass spectrometry; wherein the amount of the ion(s) detected is related to the amount of norendoxifen in said sample. |
| 地址 |
Wilmington DE US |
