| 发明名称 |
ANTINEOPLASTIC COMPOUNDS AND PHARMACEUTICAL COMPOSITIONS THEREOF |
| 摘要 |
<p>Chemical compounds identified by in silico molecular modelling, and having an structure that allows the blocking of the phosphorylation event, through the interaction of such compounds with the phosphorylation domain or its milieu in the substrates of the Casein Kinase 2 enzyme. This invention comprises also the pharmaceutical compositions containing such compounds, and their use in the preparation of medicines for the treatment of diseases related with neoplasic processes.</p> |
| 申请公布号 |
PT1892245(E) |
申请公布日期 |
2015.11.12 |
| 申请号 |
PT20060753157T |
申请日期 |
2006.05.05 |
| 申请人 |
CENTRO DE INGENIERIA GENETICA Y BIOTECNOLOGIA |
发明人 |
ROBERTO VERA ALVAREZ;ANIA DE LA NUEZ VEULENS;YULIET MAZOLA REYES;ALEXIS MUSACCHIO LASA;RAIMUNDO UBIETA GÓMEZ;ROLANDO EDUARDO RODRIGUEZ FERNANDEZ;SILVIO ERNESTO PEREA RODRÍGUEZ;BORIS ERNESTO ACEVEDO CASTRO |
| 分类号 |
C07F9/22;C07C237/30;C07C275/18;C07C275/22;C07C275/36;C07C313/06;C07C327/44;C07D207/36;C07D213/82;C07D215/18;C07D233/54;C07D235/14;C07D239/36;C07D239/42;C07D487/04 |
主分类号 |
C07F9/22 |
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