ABUSE DETERRENT IMMEDIATE RELEASE COATED RESERVOIR SOLID DOSAGE FORM

摘要

An abuse deterrent immediate release coated reservoir solid dosage form that releases the drug at a desired rate for quick onset of action when a single unit or prescribed units of the dosage form are orally administered but exhibits a reduced rate of release when more than the prescribed number of units, are administered.

主权项

1. An abuse deterrent immediate release coated reservoir solid dosage form comprising:
i) intragranular phase comprising a core containing drug susceptible to abuse and a coating comprising a reverse enteric polymer surrounding the core; ii) extragranular phase comprising the alkalizer, and wherein the reverse enteric polymer is a polymer that is soluble at an acidic pH but is insoluble at a second acidic pH of 5.5.