发明名称 |
Targeted buccal delivery comprising cisplatin-loaded chitosan nanoparticles |
摘要 |
A delivery device for topical and systemic delivery of agents to targeted oral locations, such as mouth cancer cells, has been developed. The formulation includes a mucoadhesive polymeric matrix such as chitosan, which contains one or more therapeutic and/or diagnostic agents, taste masking agents, permeation enhancers, the therapeutic or diagnostic agent to be delivered, and a hydrophilic polymeric coating such as polyethyleneglycol ("PEG"). |
申请公布号 |
AU2014218717(A1) |
申请公布日期 |
2015.11.12 |
申请号 |
AU20140218717 |
申请日期 |
2014.02.21 |
申请人 |
MASSACHUSETTS INSTITUTE OF TECHNOLOGY |
发明人 |
GOLDBERG, MANIJEH NAZARI;ALONSO, MARIA JOSE;CHEN, KUAN-JU |
分类号 |
A61K9/51;A61K9/70;A61K31/282 |
主分类号 |
A61K9/51 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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