| 主权项 |
1. A compound of Formula (I)or a pharmaceutically acceptable salt thereof, wherein:
X and X′ are each independently selected from CH, CR1, and N; Y and Y′ are each independently selected from CH, CR2, and N; provided that no more than two of X, X′, Y, and Y′ are N; R1 and R2 are independently selected from each R3 is independently selected from hydrogen, cyano, and halo; each R4 is independently selected from hydrogen, and alkyl, wherein the alkyl can optionally form a fused three- to five-membered ring with an adjacent carbon atom wherein said ring is optionally substituted with one or two methyl groups; or, R4 and the carbon to which it is attached form an ethylene group; each R5 is independently selected from hydrogen and —C(O)R6; each R6 is independently selected from alkoxy, alkyl, arylalkoxy, arylalkyl, cycloalkyl, heterocyclyl, heterocyclylalkyl, (NRcRd)alkenyl, and (NRcRd)alkyl; and each R7 and R8 is independently selected from hydrogen and alkyl. |
