发明名称 |
N-METHYLSEROTONIN AND RELATED SUBSTANCES FOR USE IN TREATING / LESSENING THE OCCURRENCE OF HOT FLASHES RELATED TO MENOPAUSE |
摘要 |
Zanthoxylum piperitum (commonly known as Japanese pepper) seeds, including its mature seeds, contain the NMS precursor/V-methylserotonin 5-O-B-glucoside (“NMS-glucoside”) present in sufficient concentration and are metabolized with sufficient efficiency so as to provide an effective amount of NMS for use in amelioration of menopausal symptoms, including hot flashes/flushes. The Japanese pepper seeds or Japanese pepper seed extracts can also be used to enrich other sources of NMS or NMS precursors in order to provide a nutraceutical or food supplement for controlling hot flashes. |
申请公布号 |
US2015320783(A1) |
申请公布日期 |
2015.11.12 |
申请号 |
US201414761834 |
申请日期 |
2014.01.24 |
申请人 |
DSM IP ASSETS B.V. |
发明人 |
BUTT Christopher Michael;WEISER Michael |
分类号 |
A61K31/7056;A23L1/30;A61K36/758 |
主分类号 |
A61K31/7056 |
代理机构 |
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代理人 |
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主权项 |
1. The use of n-methylserotonin glucoside (“NMS-glucoside”) or an NMS-precursor in an effective amount to prevent or ameliorate hot flushes associated with menopause. |
地址 |
Heerlen NL |