摘要 |
PROBLEM TO BE SOLVED: To provide compounds for the modulation of blood uric acid levels, and for the treatment of gout or hyperuricemia.SOLUTION: This invention relates to a compound expressed by the formula (I), where Ra and Rb are selected from H, halogen, C1 to C6 alkyl, or the like; M is H, C1-3 alkyl or the like; X1 is N, CH, C(halogen) or the like; X2 is N or CH; X3 is N, CH, C(halogen) or C(C1-C4 alkyl); and X4 is N or CH, wherein at least one of X1 to X4 is N; Y1 is N or CR1; Y2 is N or CR2; R1 is H, CF3, CH3, OCH3, F or Cl; and R2 is H, methyl, ethyl, propyl, isopropyl, tert-butyl, cyclopropyl, cyclobutyl, CF3, OH, OCH3, ethoxy, or the like. |