发明名称 INHALABLE COMPOSITIONS HAVING ENHANCED BIOAVAILABILITY
摘要 PROBLEM TO BE SOLVED: To provide a pharmaceutical composition for the treatment of lung cancer and the like to deliver a bioactive agent to the body by inhalation, and to provide a therapeutic method using the composition.SOLUTION: The invention provides a pharmaceutical composition containing a respirable aggregate, particles containing a lipophilic bioactive agent and at least one phospholipid, wherein the respirable aggregate has an aerodynamic mass median diameter of about 1 to about 5 μm, the lipophilic bioactive agent contains coenzyme Q10, the lipophilic bioactive agent is present in the concentration of about 15 to about 30% by weight, and the phospholipid is present in the concentration of about 2 to about 20% by weight; and a therapeutic method using the composition.
申请公布号 JP2015199765(A) 申请公布日期 2015.11.12
申请号 JP20150124479 申请日期 2015.06.22
申请人 BERG LLC 发明人 INDUSHEKHAR PERSAUD;JOHN PATRICK MCCOOK;NIVEN RAJIN NARAIN
分类号 A61K31/122;A61K9/127;A61K45/00;A61K47/24;A61K47/26;A61P11/00;A61P35/00 主分类号 A61K31/122
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