发明名称 |
TREATMENTS FOR SYSTEMIC LUPUS ERYTHEMATOSUS |
摘要 |
The disclosure involves the identification of the Eukaryotic initiation factor 4 (elF4) machinery as a downstream effector of the B-cell scaffold protein with ankyrin repeats 1 (Bankl )-mediated regulation of IL-6 expression. Thus, methods for treating patients suffering from autoimmune diseases such as systemic lupus erythematosus by targeting elF4 function are provided. |
申请公布号 |
WO2015050957(A3) |
申请公布日期 |
2015.11.12 |
申请号 |
WO2014US58576 |
申请日期 |
2014.10.01 |
申请人 |
OKLAHOMA MEDICAL RESEARCH FOUNDATION |
发明人 |
ALARCON RIQUELME, MARTA, E.;YU, YING;KUMAR, RAMESH |
分类号 |
A61K38/00;A61K31/70;A61K39/395;A61K48/00;C12N15/11 |
主分类号 |
A61K38/00 |
代理机构 |
|
代理人 |
|
主权项 |
|
地址 |
|