| 发明名称 |
FORMULATIONS OF CYCLOPHOSPHAMIDE LIQUID CONCENTRATE |
| 摘要 |
Cyclophosphamide containing compositions preferably in the form of solutions having extended stability are disclosed. The compositions contain cyclophosphamide, ethanol and an ethanol soluble acidifying agent such as citric acid. Ready to dilute or ready to use cyclophosphamide containing composition of the invention maintain high levels cyclophosphamide content after about 18 or 24 months at a temperature of about 5° C. |
| 申请公布号 |
US2015320775(A1) |
申请公布日期 |
2015.11.12 |
| 申请号 |
US201514702320 |
申请日期 |
2015.05.01 |
| 申请人 |
AuroMedics Pharma LLC |
发明人 |
PALEPU Nagesh R.;BUXTON Philip Christopher |
| 分类号 |
A61K31/664;A61K47/12;A61K47/10 |
主分类号 |
A61K31/664 |
| 代理机构 |
|
代理人 |
|
| 主权项 |
1. A cyclophosphamide containing composition having extended stability, comprising:
a) cyclophosphamide; b) ethanol; and c) an ethanol soluble acidifying agent. |
| 地址 |
Dayton NJ US |
