发明名称 |
Method for evaluating renal function |
摘要 |
<p>Plasma concentration of a compound of interest is measured in two or ideally 4 or more blood samples taken from a patient over a period of time following bolus injection. The measured values are input into a computer processor programmed to execute a computer program comprising an algorithm that uses the gamma variate (GV) function to model drug plasma concentration, then uses Tikhonov regularization to perform the fit, selecting a regularization constant so that the relative error in the plasma clearance is minimized. One or more output values representative of renal function are generated.</p> |
申请公布号 |
AU2010253887(B2) |
申请公布日期 |
2015.11.12 |
申请号 |
AU20100253887 |
申请日期 |
2010.06.01 |
申请人 |
WESOLOWSKI, CARL |
发明人 |
WESOLOWSKI, CARL A.;BABYN, PAUL;PUETTER, RICHARD |
分类号 |
G01N33/58;G01N33/60 |
主分类号 |
G01N33/58 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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