发明名称 |
CAJANINE STRUCTURE ANALOGOUS COMPOUND, PREPARATION METHOD AND USE |
摘要 |
Provided are cajanine structure analogous compounds, synthesis method and pharmacological effects thereof, the compounds of the present invention having the structure as represented by general formulas I, II, III, IV and V. Also provided are pharmaceutical compositions containing the compounds as active ingredient, and uses thereof; the compounds of the present invention having the pharmacological activities such as anti-virus, anti-virus-infection, nerve protection, anti-metabolic-diseases and the like. Also provided is a chemical total synthesis preparation method of the natural products cajanine, cajanine A and cajanine C. The present invention lays a foundation for the in-depth study and development of the compounds as clinical drugs in the future. |
申请公布号 |
EP2796442(A4) |
申请公布日期 |
2015.11.11 |
申请号 |
EP20120859858 |
申请日期 |
2012.12.18 |
申请人 |
INSTITUTE OF MEDICINAL BIOTECHNOLOGY, CHINESE ACADEMY OF MEDICAL SCIENCES |
发明人 |
LI, ZHUORONG;JI, XINGYUE;XUE, SITU;ZHENG, GUANGHUI;LI, YUHUAN;TAO, PEIZHEN;JIANG, JIANDONG |
分类号 |
C07C65/03;A61K31/192;A61P3/06;A61P3/10;A61P3/14;A61P25/00;A61P25/28;A61P31/04;A61P31/12;C07C51/09;C07C65/05;C07C65/28;C07C67/14;C07C67/16;C07C69/78;C07C69/88;C07C69/92 |
主分类号 |
C07C65/03 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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