发明名称 細胞におけるタンパク質の発現を増大させる方法
摘要 <p>The present invention relates to a method for increasing the expression of a protein in cells, preferably in eukaryotic cells, by reducing the number of RNase L cleavage sites in the coding and/or non-coding region of the nucleic acid sequence of said protein. Furthermore, it relates to nucleic acid sequences exhibiting a reduced number of RNase L cleavage sites as well as to the proteins translated from such sequences.</p>
申请公布号 JP5812287(B2) 申请公布日期 2015.11.11
申请号 JP20110545697 申请日期 2010.01.19
申请人 发明人
分类号 C12N15/09;C12N1/15;C12N1/19;C12N5/10;C12P21/02 主分类号 C12N15/09
代理机构 代理人
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