The present invention is directed to compounds and pharmaceutical formulations comprising these compounds which are useful as O-linked N-acetylglucosaminidase (O-GlcNAcase) inhibitors, and thus may be useful for the treatment of certain disorders such as Alzheimer's disease including reducing NFTs and/or hyperphosphorylated tau. The invention is also directed to use of the compounds as O-GlcNAcase imaging agents.
申请公布号
EP2847199(A4)
申请公布日期
2015.11.11
申请号
EP20130787989
申请日期
2013.05.03
申请人
MERCK SHARP & DOHME CORP.;ALECTOS THERAPEUTICS INC.